Tuesday 4 June 2024

New Video Posted: Organelles - Understanding Vesicular Transport

Cells have organelles, and they need to transport the correct molecules to those organelles — if they don't, the cell will not function correctly and will die. 

The cell has three ways of moving molecules around:

  1. Vesicular transport
  2. Gated transport
  3. Transmembrane transport
This video also looks at vesicular transport, which uses small membrane-bound sacs to move proteins, lipids, and other molecules throughout the cell.

The video introduces the concepts of Endocytosis and Exocytosis - including Phagocytosis, Pinocytosis and Receptor-Mediated Endocytosis, along with Constitutive and Regulated Pathways.

If you would like to say thanks for the fact sheet, then please feel free to buy me a coffee at https://www.buymeacoffee.com/drnickm

Blog Bonus: Free information sheet summarising the video and defining the key terms - download.

Monday 3 June 2024

New Video Posted: An introduction to cell organelles - why do cells have organelles?

In this video, I look at why cells have organelles - my answer might surprise you.

I also examine the different organelles, discuss how proteins are targeted to these organelles, and describe the mechanisms used to get proteins across membranes. 

If you would like to say thanks for the fact sheet, then please feel free to buy me a coffee at https://www.buymeacoffee.com/drnickm

Blog Bonus: Free information sheet summarising the video and defining the key terms - download.

Friday 31 May 2024

New Video Posted: Understanding Microscopy: Debunking Misconceptions in Cellular Biology

This was a fun video to make!

In this video, I use bagels to explain how some common misconceptions about the function and shape of organelles came about. I also explore, using images of horses, how we have not fully appreciated the dynamic structure of the cell and vesicle trafficking.

If you would like to say thanks for the fact sheet, then please feel free to buy me a coffee at https://www.buymeacoffee.com/drnickm

Blog Bonus: Free information sheet summarising the video and defining the key terms - download.

Thursday 30 May 2024

New Video Posted: Understanding Intermediate Filaments: Structure, Function, and Dynamics

In this video, I continue to look at the cytoskeleton by examining the structure and function of the Intermediate Filaments.

Intermediate filaments are made of various proteins (lamins, vimentin, desmin, keratin, and neurofilaments), and their composition can change depending on the cell's state. The filaments provide mechanical strength, line the nuclear membrane, and can form higher-order structures with or without accessory proteins.

If you would like to say thanks for the fact sheet, then please feel free to buy me a coffee at https://www.buymeacoffee.com/drnickm

Blog Bonus: Free information sheet summarising the video and defining the key terms - download.

Friday 24 May 2024

Science Book Catalogue

I have a growing collection of science eBooks available on the Google Play Bookstore.

Book Title and Contents
Maths and Chemistry Refresher for Life and Biomedical Scientists
Go to Download

Maths and Chemistry Refresher for Life and Biomedical Scientists

The book is a refresher for life, biomedical sciences and chemistry students who may be a little unsure of some of the key maths and chemistry skills they need and covers: Elements, atoms, ions, molecules, and compounds; Atomic weight, isotopes and molecular weight; Amounts, volumes, and concentrations; The SI units and the SI unit prefixes (m, µ, n, p etc.); Scientific Notation; Dealing with unit prefixes (m, µ, n, p etc.) in calculations; Order of operations (BODMAS and PEMDAS) in maths; How to get the best out of your calculator; Maths 'tricks' — Logs; and, graphs

Coming soon....

The big bumper book of Biomedical Sciences Terms and Definitions.

The book will contain the definitions of over 2,000 terms used in the biomedical and life sciences, along with commonly used abbreviations, molecular structures and links through to over 40 relevant videos that place the terms in context.

Tuesday 21 May 2024

New Video Posted: Understanding Microtubules: Structure, Function, and Dynamics.

I have posted the third in my series of four videos on the cytoskeleton - Understanding Microtubules: Structure, Function, and Dynamics.

In the video, I take a quick look at microtubules, one of the essential filaments that form the cytoskeleton of cells. I explore their structure, function, and dynamic nature. 

If you would like to support my blogging efforts, then please feel free to buy me a coffee at https://www.buymeacoffee.com/drnickm

Blog Bonus: Free information sheet summarising the video and defining the key terms - download.

Monday 20 May 2024

New Video Posted: Understanding Actin Filaments: Structure, Function, and Dynamics

This is the second in a series of four videos on the cytoskeleton - Understanding Actin Filaments: Structure, Function, and Dynamics.

In this video, I look at actin filaments, an essential component of the cell's cytoskeleton. 

I examine their structure, the process of filament formation, and their diverse functions in various cellular processes. I also discuss different types of actin filament structures, including contractile bundles (loose packing with myosin-II), gel-like networks (e.g., filamin), dendritic networks of branched actin molecules, and tight parallel bundles (e.g., fimbrin).

If you would like to support my blogging efforts, then please feel free to buy me a coffee at https://www.buymeacoffee.com/drnickm

Blog Bonus: Free information sheet summarising the video and defining the key terms - download.